Frequency of Acute Kidney Injury and Its Short Term Effects after Acute Myocardial Infarction
DOI:
https://doi.org/10.70749/ijbr.v3i7.1793Keywords:
Acute kidney Injury, Acute Myocardial Infarction, Atrial Fibrillation, Ventricular Tachycardia, MortalityAbstract
Objective: To determine the frequency of acute kidney injury (AKI) in patients with acute myocardial infarction (AMI) and compare the short-term outcomes between AKI and non-AKI patients. Methodology: The study was conducted at Hayatabad Medical Complex, Peshawar, from October 20, 2024 to April 21, 2025, involving 134 AMI patients. Data were collected on demographics, comorbidities, AKI status, and short-term outcomes, including ventricular tachycardia, atrial fibrillation (AF), and in-hospital mortality (VT). AKI was defined as a serum creatinine increase of 0.5 mg/dL or more within 24 hours of admission. Results: The results showed that 25.4% (34 patients) developed AKI. In comparison to the non-AKI group, the AKI group exhibited a higher in-hospital mortality rate (28.07 %) (1.79 %). The frequency of AF was 33.8% in AKI patients and 17.5% in non-AKI patients, while VT was observed in 18.5% of AKI patients and 7.5% of non-AKI patients. The statistical study did not uncover any significant connection between AKI and in-hospital mortality, AF, or VT (p-values of 0.775, 0.429, and 0.488, respectively). Conclusion: AKI is prevalent in AMI patients, with higher mortality and arrhythmia rates in the AKI group. However, no statistically significant correlation was found between AKI and short-term outcomes. Future studies should focus on multicentre data, long-term follow-up, and the role of biomarkers in predicting AKI outcomes.
Downloads
References
Becirovic, M., Bećirović, E., Hadžić, S., Rakovac Tupković, L., Bećirović, A., Avdić Jahić, N., Ribić, A., Ferhatbegović, L., Jagodić Ejubović, A., Begagić, E., Lončar, D., & Ljuca, K. (2025). Heart and kidney crosstalk: Risk factors, clinical features, and short-term outcomes associated with acute kidney injury in patients suffering acute non-ST elevation myocardial infarction. Medicinski Glasnik, 22(1), 20-25.
https://doi.org/10.17392/1776-22-01
Ali, S., Umar, R. M., Pannu, F. Y., Ali, F., Saboor, Q. A., & Ahmed, B. (2022). Frequency of acute kidney injury in patients presenting with acute ST-elevation myocardial infarction and its relationship with in-hospital mortality. Pakistan Journal of Medical and Health Sciences, 16(11), 224-227.
https://doi.org/10.53350/pjmhs20221611224
Auer, J., Verbrugge, F. H., & Lamm, G. (2017). Editor’s choice- What do small serum creatinine changes tell us about outcomes after acute myocardial infarction? European Heart Journal: Acute Cardiovascular Care, 7(8), 739-742.
https://doi.org/10.1177/2048872617728721
Menzorov, M. V., Shutov, A. M., Sakharov, V. S., & Kabanova, V. N. (2022). Acute kidney injury in acute coronary syndrome. Kazan medical journal, 103(5), 797-806.
https://doi.org/10.17816/kmj2022-797
Khoury, S., Margolis, G., Ravid, D., Rozenbaum, Z., Keren, G., & Yacov Shacham. (2020). Outcomes of early and reversible renal impairment in patients with ST segment elevation myocardial infarction undergoing percutaneous coronary intervention. European Heart Journal. Acute Cardiovascular Care, 9(7), 684–689.
https://doi.org/10.1177/2048872618808456
Marbach, J. A., Wells, G., Santo, P. D., So, D., Chong, A., Russo, J., Labinaz, M., Dick, A., Froeschl, M., Glover, C., Hibbert, B., Marquis, J., MacDougall, A., Kass, M., Paddock, V., Quraishi, A. U., Chandrasekhar, J., Ghosh, N., Bernick, J., … Le May, M. (2021). Acute kidney injury after radial or femoral artery access in ST-segment elevation myocardial infarction: AKI-SAFARI. American Heart Journal, 234, 12-22.
https://doi.org/10.1016/j.ahj.2020.12.019
Rahman, S. O., Halder, K. C., Anam, M. A., Akand, S., Aslam, M., & Rashid, M. M. (2022). Evaluation the outcome of admitted patients of acute ST elevation myocardial infarction with renal function. Saudi Journal of Medical and Pharmaceutical Sciences, 8(8), 418-422.
https://doi.org/10.36348/sjmps.2022.v08i08.008
Korostelev, A. S., Potapov, A. P., Ivanova, A. A., Hudaynazarova, К. А., Bulatov, A. V., Silina, N. N., Zakharov, P. I., & Ievleva, T. V. (2024). Acute kidney injuri of patients with acute miocard infarction. Transbaikalian Medical Bulletin, (2), 11-19.
https://doi.org/10.52485/19986173_2024_2_11
Chen, Q., Gu, Q., Yin, A., Cai, D., Xiao, T., Wang, Y., Ji, Y., Wang, Q., Wei, J., & Sun, L. (2024). Neutrophil percentage as a potential biomarker of acute kidney injury risk and short-term prognosis in patients with acute myocardial infarction in the elderly. Clinical Interventions in Aging, 19, 503-515.
https://doi.org/10.2147/cia.s455588
Marenzi, G. S., Campodonico, J., Cosentino, N., Lucci, C., Milazzo, V., Moltrasio, M., Celentano, K., Biondi, M. L., Metrio, M. D., Rubino, M., Marana, I., Grazi, M., & Lauri, G. (2020). HIGH-SENSITIVITY C-REACTIVE PROTEIN AND ACUTE KIDNEY INJURY IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION. Journal of the American College of Cardiology, 75(11), 163–163.
https://doi.org/10.1016/s0735-1097(20)30790-7
Demchuk, O. V., & Sukmanova, I. A. (2023). Acute kidney injury in patients with myocardial infarction and percutaneous coronary interventions: laboratory markers and the influence on the frequency of recurrent cardiovascular events. Complex Issues of Cardiovascular Diseases, 11(4), 25–34.
https://doi.org/10.17802/2306-1278-2022-11-4-25-34
Kumar, H., Jilanee, D., Mehta, S. M., Gul, A., Shah, S. M. H., Saleem, S., Sarfraz, M. B., Ashraf, S. U., & Wali, S. (2022). Frequency and Predictors of Acute Kidney Injury in Patients With Acute Coronary Syndrome in a Tertiary Care Hospital: A Retrospective Study. Cureus.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Indus Journal of Bioscience Research

This work is licensed under a Creative Commons Attribution 4.0 International License.
