Exploring the Nutraceutical Role of Selenium Nanoparticles on Laying Performance, Egg Attributes and Immune Response in Laying Hens

Zarnain Malik; Illahi Bakhsh Marghazani; Bahram Chachar; Qurban Ali Shah; Tahmina Shah; Biburg Mengal; Nisar Ahmed Ujjan; Muhammad Bilal

doi:10.70749/ijbr.v3i5.1365

Authors

Zarnain Malik Department of Animal Nutrition, Faculty of Veterinary and Animal Sciences, Lasbela University of Agriculture, Water and Marine Sciences Uthal, Pakistan.
Illahi Bakhsh Marghazani Department of Animal Nutrition, Faculty of Veterinary and Animal Sciences, Lasbela University of Agriculture, Water and Marine Sciences Uthal, Pakistan.
Bahram Chachar Department of Animal Nutrition, Faculty of Veterinary and Animal Sciences, Lasbela University of Agriculture, Water and Marine Sciences Uthal, Pakistan.
Qurban Ali Shah Faculty of Veterinary and Animal Sciences, Lasbela University of Agriculture, Water and Marine Sciences, Uthal, Pakistan.
Tahmina Shah Department of Biochemistry and Physiology, Shaheed Benazir Bhutto University of Veterinary and Animal Sciences, Sakrand, Sindh, Pakistan.
Biburg Mengal Department of Animal Nutrition, Faculty of Veterinary and Animal Sciences, Lasbela University of Agriculture, Water and Marine Sciences Uthal, Pakistan.
Nisar Ahmed Ujjan Faculty of Veterinary and Animal Sciences, Lasbela University of Agriculture, Water and Marine Sciences, Uthal, Pakistan.
Muhammad Bilal Disease Investigation Laboratory, Livestock and Dairy Development Department Quetta, Baluchistan, Pakistan.

DOI:

https://doi.org/10.70749/ijbr.v3i5.1365

Keywords:

Selenium nanoparticles, Laying performance, Egg characteristics, Immunity, Poultry

Abstract

Current study investigated the dose-dependent effects of dietary selenium nanoparticles (SeNPs) supplementation on productive performance, organ development, hematological parameters and humoral immunity of laying hens. A completely randomized design was employed, allocating 120 twenty-week-old White Fayoumi birds to four dietary groups (n=30 per group) receiving 0.0 (control), 0.5, 1.0, or 1.5 mg/kg SeNPs for 12-weeks of experimental period (21 to 32 weeks of age). Results demonstrated a significant (P<0.05) enhancement in live weight gain and FCR in the group supplemented with 1.0 mg/kg SeNPs compared to the control. Similarly, egg production, egg weight, yolk weight, albumen weight, shell thickness, and egg mass were significantly (P<0.05) elevated in this group. Notably, the 1.0 mg/kg SeNPs group exhibited significantly (P<0.05) increased relative weights of all examined organs. Conversely, the 1.5 mg/kg SeNPs group showed a significant (P<0.05) decline in laying performance and FCR relative to the control. While the 1.0 mg/kg SeNPs group displayed improved trends in certain blood biochemical parameters, significant differences (P<0.05) were only observed for hemoglobin levels. Importantly, supplementation with 1.0 mg/kg SeNPs significantly (P<0.05) increased serum IgM and IgA concentrations, whereas the 1.5 mg/kg SeNPs dosage significantly (P<0.05) reduced these immunoglobulin levels. In conclusion, this study elucidates a critical role for SeNPs supplementation in laying hens, with an optimal inclusion level of 1.0 mg/kg significantly improved productivity, organ development, and humoral immunity. However, exceeding this dosage (1.5 mg/kg) resulted in detrimental effects, highlighting the narrow therapeutic window and the importance of precise SeNPs administration in poultry nutrition.

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