Frequency of Hyperlipidemia among Patients of Hemorrhagic Stroke

Authors

  • Tayyaba Mumtaz Ayub Medical Complex, Abbottabad, KP, Pakistan.
  • Sana Waheed Ayub Medical Complex, Abbottabad, KP, Pakistan.
  • Muhammad Ali Javed Ayub Medical Complex, Abbottabad, KP, Pakistan.
  • Muhammad Ali Ayub Medical Complex, Abbottabad, KP, Pakistan.

DOI:

https://doi.org/10.70749/ijbr.v3i5.1224

Keywords:

Hyperlipidemia , Hemorrhagic Stroke, Diabetes, Hypertension

Abstract

Background: Increased risk for stroke is associated with hyperlipidemia for many years, particularly for ischemic stroke. However, its prevalence and association with hemorrhagic stroke are not so well known. It is important to establish the prevalence of hyperlipidemia among hemorrhagic stroke patients and its associations with clinical and demographic factors to aid stroke prevention. Objective: To determine the frequency of hyperlipidemia among patients of hemorrhagic stroke presenting at Ayub Teaching Hospital Abbottabad. Study Design: Cross-sectional study. Duration and Place of Study: The study was conducted from April 2024 to October 2024 at the Department of General Medicine, Ayub Teaching Hospital, Abbottabad. Methodology: A total of 95 patients aged 30–70 years with hemorrhagic stroke were enrolled. Hyperlipidemia was defined based on a serum cholesterol level ≥ 150 mg/dl. Data including age, gender, BMI, residential status, socioeconomic status, diabetes, and hypertension were recorded. Lipid profiles were obtained after an overnight fast. Results: The mean age of participants was 57.45 ± 8.15 years, with 68.4% male representation. Hyperlipidemia was found in 18.9% of patients. Significant associations were observed between hyperlipidemia and factors such as age (>50 years), male gender, rural residency, poor socioeconomic status, diabetes, and hypertension. Conclusion: This study highlights that while hyperlipidemia is more common in hemorrhagic stroke patients over 50 years of age.

Downloads

Download data is not yet available.

References

Ahmed, Z., Chaudhary, F., & K. Agrawal, D. (2024). Epidemiology, pathophysiology, and current treatment strategies in stroke. Cardiology and Cardiovascular Medicine, 8(4), 389-404.

https://doi.org/10.26502/fccm.92920399

Zhao, Y., Zhang, X., Chen, X., & Wei, Y. (2021). Neuronal injuries in cerebral infarction and ischemic stroke: From mechanisms to treatment (Review). International Journal of Molecular Medicine, 49(2).

https://doi.org/10.3892/ijmm.2021.5070

Saceleanu, V. M., Toader, C., Ples, H., Covache-Busuioc, R., Costin, H. P., Bratu, B., Dumitrascu, D., Bordeianu, A., Corlatescu, A. D., & Ciurea, A. V. (2023). Integrative approaches in acute ischemic stroke: From symptom recognition to future innovations. Biomedicines, 11(10), 2617.

https://doi.org/10.3390/biomedicines11102617

Abdu, H., Tadese, F., & Seyoum, G. (2021). Comparison of ischemic and hemorrhagic stroke in the medical ward of Dessie referral hospital, Northeast Ethiopia: A retrospective study. Neurology Research International, 2021, 1-9. https://doi.org/10.1155/2021/9996958

Magid-Bernstein, J., Girard, R., Polster, S., Srinath, A., Romanos, S., Awad, I. A., & Sansing, L. H. (2022). Cerebral hemorrhage: Pathophysiology, treatment, and future directions. Circulation Research, 130(8), 1204-1229.

https://doi.org/10.1161/circresaha.121.319949

10th European stroke organisation conference abstracts – 15-17 May 2024, Basel, Switzerland. (2024). European Stroke Journal, 9(1_suppl), 3-647.

https://doi.org/10.1177/23969873241245672

Wazir, M., Olanrewaju, O. A., Yahya, M., Kumari, J., Kumar, N., Singh, J., Abbas Al-itbi, A. Y., Kumari, K., Ahmed, A., Islam, T., Varrassi, G., Khatri, M., Kumar, S., Wazir, H., & Raza, S. S. (2023). Lipid disorders and cardiovascular risk: A comprehensive analysis of current perspectives. Cureus.

https://doi.org/10.7759/cureus.51395

Liang, H., Zhang, Q., Hu, Y., Liu, G., & Qi, R. (2022). Hypertriglyceridemia: A neglected risk factor for ischemic stroke? Journal of Stroke, 24(1), 21-40.

https://doi.org/10.5853/jos.2021.02831

Das, P., & Ingole, N. (2023). Lipoproteins and their effects on the cardiovascular system. Cureus.

https://doi.org/10.7759/cureus.48865

Alloubani, A., Nimer, R., & Samara, R. (2021). Relationship between hyperlipidemia, cardiovascular disease andStroke: A systematic review. Current Cardiology Reviews, 17(6).

https://doi.org/10.2174/1573403x16999201210200342

Heydari, F., Tajvidi, M., Mohammadi, S. M., Kamyari, N., Mohammadshahi, F., Maleki, H., Zeinivand, N., Radmanesh, E., & Pakzad, R. (2025). Investigation of lipid profile in patients with cerebrovascular diseases: Systematic review and meta-analysis. Advanced Biomedical Research, 14(1).

https://doi.org/10.4103/abr.abr_360_23

Jebari-Benslaiman, S., Galicia-García, U., Larrea-Sebal, A., Olaetxea, J. R., Alloza, I., Vandenbroeck, K., Benito-Vicente, A., & Martín, C. (2022). Pathophysiology of atherosclerosis. International Journal of Molecular Sciences, 23(6), 3346.

https://doi.org/10.3390/ijms23063346

Alkhaneen, H., Alsadoun, D., Almojel, L., Alotaibi, A., & Akkam, A. (2022). Differences of lipid profile among ischemic and hemorrhagic stroke patients in a tertiary hospital in Riyadh, Saudi Arabia: A retrospective cohort study. Cureus.

https://doi.org/10.7759/cureus.25540

Taimuri, B. A., Malik, A., Muhammad, R. S., & Javed, M. (2023). Frequency of hyperlipidemia in patients with ischemic stroke visiting at a tertiary care hospital in Karachi. Pakistan Journal of Neurological Sciences, 18(02).

https://doi.org/10.56310/pjns.v18i02.265

Gul, M. M., Ali, W., Iqbal, S., Bano, M., Memon, A., & Hussain, W. A. J. I. D. (2021). Frequency of dyslipidemia in patients presented with ischemic stroke. Age (years), 35(34), 17.

https://pjmhsonline.com/2021/april/1212.pdf

Aslam, M. S. (2017). Pattern of dyslipidemias and their association with ischemic and hemorrhagic stroke. Journal of Islamabad Medical & Dental College, 6(3), 134-139.

https://jimdc.org.pk/index.php/JIMDC/article/view/38

Bhatti, K. A., & Kumar, S. (2016). Prevalence of Hyperlipidemia in Adult Stroke Patient at Liaquat University Hospital Jamshoro, Sindh. Journal of Liaquat University of Medical & Health Sciences, 15(3).

Batool, S. N., Qader, A. A., Mehmood, K., Zareen, S. F., Khan, H. U., & Shafique, H. (2024). Lipid Profile in Stroke Patients Presenting in Emergency Department: Lipid Profile in Stroke Patients. Journal of Health and Rehabilitation Research, 4(3), 1-5.

https://doi.org/10.61919/jhrr.v4i3.1624

Nasim, H., Butt, N. I., Ashfaq, F., Anwar, A., Aftab, S., & Muaaz, M. (2023). Frequency of modifiable risk factors in ischemic stroke patients at a tertiary care hospital in Lahore Pakistan. Pakistan Journal of Medical Research, 62(2), 53-58.

https://pjmr.org.pk/index.php/pjmr/article/view/405

Downloads

Published

2025-05-08

How to Cite

Mumtaz, T., Waheed, S., Javed, M. A., & Ali, M. (2025). Frequency of Hyperlipidemia among Patients of Hemorrhagic Stroke. Indus Journal of Bioscience Research, 3(5), 149–153. https://doi.org/10.70749/ijbr.v3i5.1224