The Effect of Comorbid Conditions on Mortality in Patients Undergoing Percutaneous Coronary Intervention
DOI:
https://doi.org/10.70749/ijbr.v3i5.1212Keywords:
Percutaneous Coronary Intervention, Comorbidities, Mortality, Heart Failure, Chronic Kidney Disease, COPD, Charlson Comorbidity IndexAbstract
Introduction: Percutaneous coronary intervention (PCI) forms a standard treatment approach for coronary artery disease (CAD), while comorbid conditions produce considerable effects on patient results. Research determines how comorbidities affect the survival rates of patients who receive PCI. Objective: The research aims to determine how comorbidities affect the death rates of patients who receive PCI both during hospitalization and in the long-term. Materials and Method: A retrospective cohort research took place at Department of Cardiology, Hayatabad Medical Complex, Peshawar from January, 2022 to June of 2022. The study examined a total of 150 PCI patients' medical information including their diagnoses of heart failure and chronic kidney disease and COPD. The research used mortality data in combination with the Charlson Comorbidity Index (CCI) for measuring patient outcomes. Results: The mortality rate in hospitals reached 5.3%, while patients who had both heart failure and chronic kidney disease experienced the highest risk factors. Long-term mortality data computed 3.6% death amongst all patients, though COPD and kidney disease combination increased fatality rates. Conclusion: Healthcare providers need a unique treatment approach to care for PCI patients before their procedure because their coexisting illnesses raise the possibility of hospital deaths and reduced long-term survival chances.
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Castro-Dominguez, Y.S., Wang, Y., Minges, K.E., McNamara, R.L., Spertus, J.A., Dehmer, G.J., Messenger, J.C., Lavin, K., Anderson, C., Blankinship, K. and Mercado, N., 2021. Predicting in-hospital mortality in patients undergoing percutaneous coronary intervention. Journal of the American College of Cardiology, 78(3), pp.216-229.
https://doi.org/10.1016/j.jacc.2021.04.067
Singh, M., Gulati, R., Lewis, B.R., Zhou, Z., Alkhouli, M., Friedman, P. and Bell, M.R., 2022. Multimorbidity and mortality models to predict complications following percutaneous coronary interventions. Circulation: Cardiovascular Interventions, 15(7), p.e011540.
https://doi.org/10.1161/circinterventions.121.011540
Yi, Y.A.O., Pei, Z.H.U., Na, X.U., Xiao-Fang, T.A.N.G., Ying, S.O.N.G., Xue-Yan, Z.H.A.O., Shu-Bin, Q.I.A.O., Yue-Jin, Y.A.N.G., Jin-Qing, Y.U.A.N. and Run-Lin, G.A.O., 2022. Effects of chronic obstructive pulmonary disease on long-term prognosis of patients with coronary heart disease post-percutaneous coronary intervention. Journal of Geriatric Cardiology: JGC, 19(6), p.428.
Parikh, P.B., Bhatt, D.L., Bhasin, V., Anker, S.D., Skopicki, H.A., Claessen, B.E., Fonarow, G.C., Hernandez, A.F., Mehran, R., Petrie, M.C. and Butler, J., 2021. Impact of percutaneous coronary intervention on outcomes in patients with heart failure: JACC state-of-the-art review. Journal of the American College of Cardiology, 77(19), pp.2432-2447.
https://doi.org/10.1016/j.jacc.2021.03.310
Chen, L., Huang, Z., Lu, J., Yang, Y., Pan, Y., Bao, K., Wang, J., Chen, W., Liu, J., Liu, Y. and Chen, K., 2021. Impact of the malnutrition on mortality in elderly patients undergoing percutaneous coronary intervention. Clinical Interventions in Aging, pp.1347-1356.
https://doi.org/10.2147/cia.s308569
Buckley, B.J., De Koning, I.A., Harrison, S.L., Fazio-Eynullayeva, E., Underhill, P., Kemps, H.M., Lip, G.Y. and Thijssen, D.H., 2022. Exercise-based cardiac rehabilitation vs. percutaneous coronary intervention for chronic coronary syndrome: impact on morbidity and mortality. European Journal of Preventive Cardiology, 29(7), pp.1074-1080.
https://doi.org/10.1093/eurjpc/zwab191
Hanna, J.M., Wang, S.Y., Kochar, A., Park, D.Y., Damluji, A.A., Henry, G.A., Ahmad, Y., Curtis, J.P. and Nanna, M.G., 2023. Complex percutaneous coronary intervention outcomes in older adults. Journal of the American Heart Association, 12(19), p.e029057.
https://doi.org/10.1161/jaha.122.029057
Li, Y., Zheng, H., Yan, W., Cao, N., Yan, T., Zhu, H. and Bao, H., 2023. The impact of chronic obstructive pulmonary disease on the prognosis outcomes of patients with percutaneous coronary intervention or coronary artery bypass grafting: A meta-analysis. Heart & Lung, 60, pp.8-14.
https://doi.org/10.1016/j.hrtlng.2023.02.017
Lee, C.W., Lee, J.K., Choi, Y.J., Kim, H., Han, K., Jung, J.H., Kim, D.H. and Park, J.H., 2022. Blood pressure and mortality after percutaneous coronary intervention: a population-based cohort study. Scientific Reports, 12(1), p.2768.
https://doi.org/10.1038/s41598-022-06627-4
Choi, B.G., Hong, J.Y., Rha, S.W., Choi, C.U. and Lee, M.S., 2021. Long-term outcomes of peripheral arterial disease patients with significant coronary artery disease undergoing percutaneous coronary intervention. Plos one, 16(5), p.e0251542.
https://doi.org/10.1371/journal.pone.0251542
Matta, A.G., Lhermusier, T., Parada, F.C., Bouisset, F., Canitrot, R., Nader, V., Blanco, S., Elbaz, M., Roncalli, J. and Carrié, D., 2021. Impact of coronary artery disease and percutaneous coronary intervention on transcatheter aortic valve implantation. Journal of interventional cardiology, 2021(1), p.6672400.
https://doi.org/10.1155/2021/6672400
Conradie, A., Atherton, J., Chowdhury, E., Duong, M., Schwarz, N., Worthley, S. and Eccleston, D., 2022. Health-related quality of life (HRQoL) and the effect on outcome in patients presenting with coronary artery disease and treated with percutaneous coronary intervention (PCI): differences noted by sex and age. Journal of Clinical Medicine, 11(17), p.5231.
https://doi.org/10.3390/jcm11175231
Yıldırım, A., Kucukosmanoglu, M., Koyunsever, N.Y., Cekici, Y., Belibagli, M.C. and Kılıc, S., 2021. Combined effects of nutritional status on long-term mortality in patients with non-st segment elevation myocardial infarction undergoing percutaneous coronary intervention. Revista da Associação Médica Brasileira, 67(2), pp.235-242.
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