Perinatal outcome in Patients Presented with Antepartum Hemorrhage

Authors

  • Raheen Imtiaz Ayub Teaching Hospital, Abbottabad, KP, Pakistan.
  • Kiran Idrees Ayub Teaching Hospital, Abbottabad, KP, Pakistan.
  • Jawairia Samee Ayub Teaching Hospital, Abbottabad, KP, Pakistan.
  • Hajra Ali Qureshi Ayub Teaching Hospital, Abbottabad, KP, Pakistan.

DOI:

https://doi.org/10.70749/ijbr.v3i5.1552

Keywords:

Antepartum Hemorrhage, Low Birth Weight, Stillbirth, Neonatal Death

Abstract

Background: Antepartum hemorrhage is an obstetric complication that can result in unfavorable maternal and perinatal outcomes. Identification and management of APH play an important role in enhancing the survival rates among mothers and neonates. Several factors, such as gestational age, parity, and placental pathology, influence the outcome in cases of APH, yet their association with complication severity is intricate and not fully investigated. Objective: To determine the frequency of perinatal outcomes in patients presenting with antepartum hemorrhage. Study Design: Descriptive cross-sectional study. Duration and Place of Study: The study was conducted from April 2024 to October 2024 at the Department of Obstetrics and Gynaecology, ATH Abbottabad. Methodology: The study included 113 women aged 18-40 years with singleton pregnancies of more than 28 weeks gestation, who presented with APH. Demographic data, including age, gestational age, parity, BMI, and residential status, were recorded. Patients were monitored for perinatal outcomes such as low birth weight, stillbirth, and neonatal death. Results: The study found that 38.9% of participants had low birth weight, 20.4% experienced stillbirth, and 14.2% had neonatal death. Stratified analyses showed that gestational age ≤35 weeks was significantly associated with low birth weight, with a p-value of 0.004. Parity was also significantly associated with low birth weight, as women with fewer previous pregnancies had a higher incidence of low birth weight (p-value = 0.013). For stillbirth, a significant association was found with gestational age ≤35 weeks (p-value = 0.012), but no significant association was found with parity (p-value = 0.213). Conclusion: Our study concludes that antepartum hemorrhage remains a major determinant of adverse maternal and perinatal outcomes.

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References

Battula, S. P., Mohammed, N. H., & Datta, S. (2021). Antepartum haemorrhage. Obstetrics, Gynaecology & Reproductive Medicine, 31(4), 117-123.

https://doi.org/10.1016/j.ogrm.2021.02.001

Im, D. H., Kim, Y. N., Cho, E. H., Kim, D. H., Byun, J. M., & Jeong, D. H. (2023). Risk factors and pregnancy outcomes of Antepartum hemorrhage in women with placenta Previa. Reproductive Sciences, 30(9), 2728-2735.

https://doi.org/10.1007/s43032-023-01191-2

Dinho, A. E., Mårtensson, L. B., Georgsson, M., Laisser, R., & Knutsson, S. (2024). Tanzanian midwives’ clinical practices and experiences in caring for women with antepartum hemorrhage: A critical incident technique study. BMC Pregnancy and Childbirth, 24(1).

https://doi.org/10.1186/s12884-024-06802-7

Okunade, K. S., Oyedeji, O. A., Olowoselu, O. F., Adejimi, A., Ademuyiwa, I., Olumodeji, A. M., Adelabu, H., Ugwu, A., Adenekan, M., & Oluwole, A. A. (2024). Incidence and Antepartum risk factors of severe postpartum haemorrhage in anaemic pregnant women in Lagos, Nigeria: A secondary cohort analysis. Cureus.

https://doi.org/10.7759/cureus.54980

Ayele, T. B., & Moyehodie, Y. A. (2023). Prevalence of preterm birth and associated factors among mothers who gave birth in public hospitals of east Gojjam zone, Ethiopia. BMC Pregnancy and Childbirth, 23(1).

https://doi.org/10.1186/s12884-023-05517-5

Agarwal, S., Ranjan, M., Sachan, S., & Kumar, L. (2023). Antepartum hemorrhage and its maternal and perinatal outcome: An experience at a hospital in North India. Journal of Family Medicine and Primary Care, 12(12), 3204-3208.

https://doi.org/10.4103/jfmpc.jfmpc_692_23

Matar, M., Yared, G., Massaad, C., & Ghazal, K. (2025). Vaginal bleeding during pregnancy: A retrospective cohort study assessing maternal and perinatal outcomes. Journal of International Medical Research, 53(2).

https://doi.org/10.1177/03000605251315349

Oguejiofor, C., Okafor, C., Eleje, G., Ikechebelu, J., Okafor, C., Ugboaja, J., Ogabido, C., Njoku, T., Umeononihu, O., Okpala, B., Nwankwo, M., Ezeigwe, C., Enechukwu, C., & Eke, A. (2023). A five-year review of feto-maternal outcome of Antepartum haemorrhage in a tertiary center in Nigeria. International Journal of Innovative Research in Medical Science, 8(03), 96-101.

https://doi.org/10.23958/ijirms/vol08-i03/1637

Danieli-Gruber, S., Shalev-Rosenthal, Y., Matot, R., Brzezinski-Sinai, N., Zeevi, G., Pardo, A., Orbach, S., & Hadar, E. (2023). Risks of urgent cesarean delivery preceding the planned schedule: A retrospective cohort study. PLOS ONE, 18(8), e0289655.

https://doi.org/10.1371/journal.pone.0289655

Abraha, T. A., Gebremariam, G. K., Asfaha, B. T., Weldegebreal, T. K., & Aregawi, D. H. (2025). Adverse birth outcome and associated factors among mothers with antepartum hemorrhage in public hospitals Tigray, northern Ethiopia, 2020. BMC Pregnancy and Childbirth, 25(1).

https://doi.org/10.1186/s12884-025-07216-9

Erez, O., Othman, M., Rabinovich, A., Leron, E., Gotsch, F., & Thachil, J. (2022). DIC in pregnancy – Pathophysiology, clinical characteristics, diagnostic scores, and treatments. Journal of Blood Medicine, 13, 21-44.

https://doi.org/10.2147/jbm.s273047

Fan, D., Hu, P., Rao, J., Lin, D., Yang, J., Liu, Z., & Guo, X. (2025). Prediction nomogram for antepartum hemorrhage in placenta previa women. Therapeutic Advances in Reproductive Health, 19.

https://doi.org/10.1177/26334941251315127

Jańczewska, I., Wierzba, J., Jańczewska, A., Szczurek-Gierczak, M., & Domżalska-Popadiuk, I. (2023). Prematurity and low birth weight and their impact on childhood growth patterns and the risk of long-term cardiovascular sequelae. Children, 10(10), 1599.

https://doi.org/10.3390/children10101599

Kebede, E., & Kekulawala, M. (2021). Risk factors for stillbirth and early neonatal death: A case-control study in tertiary hospitals in Addis Ababa, Ethiopia. BMC Pregnancy and Childbirth, 21(1).

https://doi.org/10.1186/s12884-021-04025-8

Jovanovic, I., Ivanovic, K., Kostic, S., Tadic, J., Dugalic, S., Petronijevic, M., Gojnic, M., Petronijevic, M., & Vrzic-Petronijevic, S. (2023). Intrauterine fetal death in term pregnancy—A single tertiary clinic study. Life, 13(12), 2320.

https://doi.org/10.3390/life13122320

Agarwal, R., & Agrawal, R. (2024). Exploring risk factors and perinatal outcomes of preterm birth in a tertiary care hospital: A comprehensive analysis. Cureus.

https://doi.org/10.7759/cureus.53673

Dahri, B., Taj, I., Taj, A., Nadeem, T., & Nisa, K. (2022). Perinatal outcome in patients of Antepartum haemorrhage. Pakistan Journal of Medical and Health Sciences, 16(12), 742-744.

https://doi.org/10.53350/pjmhs20221612742

Rathi, B. A. (2020). Clinical study of maternal and perinatal outcome in antepartum haemorrhage at a tertiary care institute. MedPulse International Journal of Gynaecology, 16(3), 39-42.

https://doi.org/10.26611/10121633

Jharaik, H., Sharma, A., Dhiman, B., & Sharma, K. (2019). Consequences of antepartum haemorrhage and its perinatal outcome. International Journal of Clinical Obstetrics and Gynaecology, 3(3), 155-159.

https://doi.org/10.33545/gynae.2019.v3.i3c.276

Jain, S., Jain, N., Dahiya, P., Rohilla, S., & Malik, R. (2016). A prospective study of maternal outcome in antepartum haemorrhage in tertiary care center in northern India. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 29-34.

https://doi.org/10.18203/2320-1770.ijrcog20151493

Kulkarni, A. R., & Shirsath, A. S. (2021). Study of antepartum hemorrhage and its maternal and perinatal outcome at a tertiary care hospital. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 10(6), 2210.

https://doi.org/10.18203/2320-1770.ijrcog20212149

Mushtaq, R., Abbas, A., & Ahmed, W. (2019). Perinatal outcomes in pregnant patients presenting with antepartum hemorrhage: Our experiences at a teaching hospital in central Punjab. The Professional Medical Journal, 26(10), 1645-1650.

https://doi.org/10.29309/tpmj/2019.26.10.3152

Behera, R, Dash, S, Jena, S, Sahoo, M, Nath, J, & Panigrahy R. (2022). Maternal & perinatal outcome in antepartum hemorrhage. J Popul Ther Clin Pharmacol. 29(4), 839-843.

https://doi.org/10.53555/jptcp.v29i04.3394

Anjankar, P. S., & Ramteke, S. (2022). Maternal and perinatal outcome in antepartum haemorrhage patients attending tertiary care hospital in central India: A prospective observational study. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 11(11), 2997.

https://doi.org/10.18203/2320-1770.ijrcog20222616

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Published

2025-05-31

How to Cite

Imtiaz, R., Idrees, K., Samee, J., & Qureshi, H. A. (2025). Perinatal outcome in Patients Presented with Antepartum Hemorrhage. Indus Journal of Bioscience Research, 3(5), 924–928. https://doi.org/10.70749/ijbr.v3i5.1552

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