Clinical Long-Term Complications of Post Covid Time in Patients Reporting at PAF Hospital Within 3 Months After Discharge

Authors

  • Javaria Mehtab Department of Medicine, PAF Hospital, Islamabad, Pakistan.
  • Asif Niaz HOD, Department of Medicine, PAF Hospital, Islamabad, Pakistan.
  • Nabeeha Azhar Department of Medicine, PAF Hospital, Islamabad, Pakistan.
  • Mahnoor Khawaja Department of Medicine, PAF Hospital, Islamabad, Pakistan.

DOI:

https://doi.org/10.70749/ijbr.v3i5.1190

Keywords:

Post COVID-19 time, Dyspnea, Fatigue, Long term complications

Abstract

Objectives: To determine the long term complications of post COVID time in patients reporting within 3 months after discharge. Study design: Cross-sectional study. Place and duration of study: Department of Medicine, PAF Hospital, Islamabad. From July 2021 to June 2022. Methods: A total of 100 patients, ≥ 18 years of age, with a confirmed diagnosis of COVID-19 infection and admission to the hospital, presenting to the outpatient department within 3 months of hospital discharge were enrolled in this study.  All the related demographics were noted and details of medical history was taken from patient’s medical record. Clinical symptoms were recorded using a standard questionnaire and grouped as respiratory, musculoskeletal, cardiovascular, neurological, gastrointestinal and psychological functions to determine the full spectrum of post-COVID sequelae. Results: Mean age of patients in this study was 53.88±8.03 years with an age range of 39 to 67 years. Males were 57% of total study population while females were 43%. The details of clinical symptoms reported by these patients showed that fatigue (59%), dyspnea (47%) and loss of taste/smell (41%) were the most frequent symptoms reflecting COVID-19 complications associated with musculoskeletal, respiratory and neurological functions. Conclusion: COVID-19 patients reporting within 3 months of discharge from hospitalization still experience fatigue, dyspnea, and loss of taste/smell, indicating respiratory, musculoskeletal and neurological complications even after recovery from this infection.

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References

Cascella M, Rajnik M, Aleem A, et al. Features, Evaluation, and Treatment of Coronavirus (COVID-19) [Updated 2023 Aug 18]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-

https://www.ncbi.nlm.nih.gov/books/NBK554776/

National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Board on Global Health; Board on Health Sciences Policy; Committee on Examining the Working Definition for Long COVID; Goldowitz I, Worku T, Brown L, et al., editors. A Long COVID Definition: A Chronic, Systemic Disease State with Profound Consequences. Washington (DC): National Academies Press (US); 2024 Jul 9. 1, Introduction. https://www.ncbi.nlm.nih.gov/books/NBK605678/

Nalbandian A, Sehgal K, Gupta A, Madhavan MV, McGroder C, Stevens JS, et al. Post-acute COVID-19 syndrome. Nat Med. 2021;27(4):601-15.

https://doi.org/ 10.1038/s41591-021-01283-z.

Mann R, Perisetti A, Gajendran M, Gandhi Z, Umapathy C, Goyal H. Clinical Characteristics, Diagnosis, and Treatment of Major Coronavirus Outbreaks. Front Med (Lausanne). 2020;7:581521. https://doi.org/10.3389/fmed.2020.581521.

O'Sullivan O. Long-term sequelae following previous coronavirus epidemics. Clin Med (Lond). 2021;21(1):e68-e70. https://doi.org/10.7861/clinmed.2020-0204.

Ciaffi J, Vanni E, Mancarella L, Brusi V, Lisi L, Pignatti F, et al. Post-Acute COVID-19 Joint Pain and New Onset of Rheumatic Musculoskeletal Diseases: A Systematic Review. Diagnostics (Basel). 2023;13(11):1850.

https://doi.org/10.3390/diagnostics13111850.

Lucidi D, Molinari G, Silvestri M, De Corso E, Guaraldi G, Mussini C, Presutti L, Fernandez IJ. Patient-reported olfactory recovery after SARS-CoV-2 infection: A 6-month follow-up study. Int Forum Allergy Rhinol. 2021.11(8):1249-1252.

https://doi.org/10.1002/alr.22775.

Xu Z, Shi L, Wang Y, Zhang J, Huang L, Zhang C, et al. Pathological findings of COVID-19 associated with acute respiratory distress syndrome. Lancet Respir Med. 2020;8(4):420-422. https://doi.org/10.1016/S2213-2600(20)30076-X.

Mo X, Jian W, Su Z, Chen M, Peng H, Peng P, et al. Abnormal pulmonary function in COVID-19 patients at time of hospital discharge. Eur Respir J. 2020;55(6):2001217. https://doi.org/10.1183/13993003.01217-2020.

Bellan M, Soddu D, Balbo PE, Baricich A, Zeppegno P, Avanzi GC, et al. Respiratory and Psychophysical Sequelae Among Patients With COVID-19 Four Months After Hospital Discharge. JAMA Netw Open. 2021;4(1):e2036142.

https://doi.org/10.1001/jamanetworkopen.2020.36142.

Bilgin S, Yamanpglu A, Kayali A, Payza U, Efgan MG, Cinaroglu OS, et al. Long COVID symptoms among outpatients with COVID-19: a descriptive study. Cukurova Med J. 2023;48(1):243-52.

https://doi.org/10.17826/cumj.1216943.

Singh TK, Zidar DA, McCrae K, Highland KB, Englund K, Cameron SJ, et al. A Post-Pandemic Enigma: The Cardiovascular Impact of Post-Acute Sequelae of SARS-CoV-2. Circ Res. 2023;132(10):1358-1373. https://doi.org/10.1161/CIRCRESAHA.122.322228.

Dryden M, Mudara C, Vika C, Blumberg L, Mayet N, Cohen C, et al. Post-COVID-19 condition 3 months after hospitalisation with SARS-CoV-2 in South Africa: a prospective cohort study. Lancet Glob Health. 2022;10(9):e1247-e1256.

https://doi.org/10.1016/S2214-109X(22)00286-8.

Grewal JS, Carlsten C, Johnston JC, Shah AS, Wong AW, Ryerson CJ. Post-COVID dyspnea: prevalence, predictors, and outcomes in a longitudinal, prospective cohort. BMC Pulm Med. 2023;23(1):84.

https://doi.org/10.1186/s12890-023-02376-w.

Huang C, Huang L, Wang Y, Li X, Ren L, Gu X, et al. 6-month consequences of COVID-19 in patients discharged from hospital: a cohort study. Lancet. 2023;401(10393):e21-e33. https://doi.org/10.1016/S0140-6736(23)00810-3.

Chopra V, Flanders SA, O'Malley M, Malani AN, Prescott HC. Sixty-Day Outcomes Among Patients Hospitalized With COVID-19. Ann Intern Med. 2021;174(4):576-8.

https://doi.org/10.7326/M20-5661.

Zhao YM, Shang YM, Song WB, Li QQ, Xie H, Xu QF, et al. Follow-up study of the pulmonary function and related physiological characteristics of COVID-19 survivors three months after recovery. EClinicalMedicine. 2020;25:100463.

https://doi.org/10.1016/j.eclinm.2020.100463.

Qamar MA, Martins RS, Dhillon RA, Tharwani A, Irfan O, Suriya QF, et al. Residual symptoms and the quality of life in individuals recovered from COVID-19 infection: A survey from Pakistan. Ann Med Surg. 2022;75:103394.

https://doi.org/10.1016/j.amsu.2022.103361.

Wu L, Wu Y, Xiong H, Mei B, You T. Persistence of Symptoms After Discharge of Patients Hospitalized Due to COVID-19. Front Med (Lausanne). 2021;8:761314.

https://doi.org/10.3389/fmed.2021.761314.

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Published

2025-05-09

How to Cite

Mehtab, J., Niaz, A., Azhar, N., & Khawaja, M. (2025). Clinical Long-Term Complications of Post Covid Time in Patients Reporting at PAF Hospital Within 3 Months After Discharge. Indus Journal of Bioscience Research, 3(5), 220–224. https://doi.org/10.70749/ijbr.v3i5.1190