Impact of Door-To-Balloon Time on Long-Term Mortality after Primary PCI

Authors

  • Muhammad Niaz Khan Department of Cardiology, Hayatabad Medical Complex Peshawar, Pakistan
  • Hamid Ali Shah Department of Cardiology, Hayatabad Medical Complex Peshawar, Pakistan
  • Nasir Ali Department of Cardiology, Hayatabad Medical Complex Peshawar, Pakistan
  • Amir Rashid Qureshi Department of Cardiology, Hayatabad Medical Complex Peshawar, Pakistan
  • Abid Ullah Department of Cardiology, Hayatabad Medical Complex Peshawar, Pakistan
  • Muhammad Salman Department of Cardiology, Hayatabad Medical Complex Peshawar, Pakistan

DOI:

https://doi.org/10.70749/ijbr.v2i02.224

Keywords:

STEMI, Door-To-Balloon Time, Primary PCI, Mortality, Major Adverse Cardiovascular Events

Abstract

Objective:  To evaluate the impact of door-to-balloon (D2B) time on long-term mortality and adverse outcomes in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI) at Hayatabad Medical Complex, Peshawar.

Methodology:  A prospective observational study was conducted from January 2022 to December 2022, including 320 STEMI patients. Patients were categorized into two groups based on D2B times: <90 minutes and ≥90 minutes. Data on demographics, symptom-to-door times, D2B times, and outcomes (mortality and major adverse cardiovascular events (MACE)) were collected. Statistical analysis was performed using appropriate tests, with a significance level of p<0.05.

Results:  The mean symptom-to-door time was 145.6 minutes, and the mean D2B time was 96.7 minutes. Patients treated within <90 minutes of D2B time had a survival rate of 91.3% compared to 73.4% in the ≥90-minute group (p<0.05). MACE occurred in 12.5% of patients, with a higher prevalence in those with delayed D2B times. Male patients constituted 62.5% of the cohort, and the mean age was 54.3 years.

Conclusion:  Shorter D2B times significantly improve survival and reduce adverse outcomes in STEMI patients. Adhering to the recommended <90 minutes for D2B is essential for optimizing clinical outcomes. Systemic changes to reduce delays are imperative for improving STEMI care.

 

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Published

2024-11-20

How to Cite

Khan, M. N., Ali Shah , H., Ali , N., Rashid Qureshi, A., Ullah , A., & Muhammad Salman. (2024). Impact of Door-To-Balloon Time on Long-Term Mortality after Primary PCI. Indus Journal of Bioscience Research, 2(02), 488–493. https://doi.org/10.70749/ijbr.v2i02.224