Pattern of Coronary Artery Diseases (CAD) in patients under 40 Years of Age with Acute Coronary Syndrome (ACS)

Khadija Sarwat Farooqui; Zakra Batool; Romaza Muneer; Khawaja Abdullah Zahid; Muhammad Hamza Riaz; Amna Attiq

doi:10.70749/ijbr.v2i02.208

Authors

Khadija Sarwat Farooqui Emergency Department, NICVD Karachi, Pakistan
Zakra Batool Department of Medicine, Pakistan Institute of Medical Sciences, Islamabad (PIMS), Pakistan
Romaza Muneer Department of Medicine, Pakistan Institute of Medical Sciences, Islamabad (PIMS), Pakistan
Khawaja Abdullah Zahid Department of Cardiology, Bahauddin Cardiac Complex, Mandi Bahauddin, Pakistan
Muhammad Hamza Riaz Department of Medicine, Social Security Hospital, Gujranwala, Pakistan
Amna Attiq Department of Nephrology, Hamad Medical Corporation, Qatar.

DOI:

https://doi.org/10.70749/ijbr.v2i02.208

Keywords:

Coronary artery disease, Acute Coronary Syndrome, Young Adults, Angiographic Patterns, Risk Factors, Single-Vessel Disease

Abstract

Objectives

To assess angiographic patterns, risk factor profile, and outcome of patients below 40 years of age with acute coronary syndrome undergoing coronary angiography for confirmed CAD.

Materials and Methods

The present study was an analytical cross-sectional study in a tertiary care hospital, and all the participants were ≤40 years old with new-onset ACS. Demographic variables, cardiovascular risk factors, and angiographic characteristics were assessed. They were evaluated for other cardiovascular risk factors and stratified according to the patterns of CAD on angiography.

Results

Depending on the localization of atherosclerotic lesions, 72% of patients were characterized by single-vessel coronary involvement with predominant damage to the left anterior descending artery. A smoking history, 68% dyslipidemia, 59% known history of CAD in first-degree relatives, and 52% were the most common risk factors. Most patients had normal left ventricular systolic performance. Nevertheless, 16% of patients would have poor follow-up results.

Conclusion

The majority of young patients with ACS have single-vessel CAD, and conventional atherosclerotic risk factors contribute to the development of early-onset CAD. Prevention strategies, as well as CAD screening in this age group, are critical to avoid high incidences within this group.

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