Unraveling of Multifactorial Etiology and Risk Factors of Severe Anemia HB ≤ 6 g/dL

Authors

  • Easha-Tur-Razia Department of Medicine, Abbas Institute of Medical Sciences, Muzaffarabad, AJK, Pakistan.
  • Sara Arshad Khan Department of Medicine, Abbas Institute of Medical Sciences, Muzaffarabad, AJK, Pakistan.
  • Abdul Khalid Awan Department of Medicine, Abbas Institute of Medical Sciences, Muzaffarabad, AJK, Pakistan.

DOI:

https://doi.org/10.70749/ijbr.v2i02.157

Keywords:

Anemia, Hemoglobin, Iron Deficiency, Vitamin B12

Abstract

 

Background: Anemia is an alarming worldwide health condition affecting individuals from modernized and countries that underdeveloped, with significant implications for human health and socio-economic development.

Aims: This research aimed to find the primary risk factors linked with severe anemia (HB ≤ 6 g/dL) and assess the relative contribution of different factors, including nutritional status, chronic diseases, infections, and genetic factors.

Methodology: A cross-sectional study investigated the fundamental causes and risk factors of disease anemia (HB≤ 6 g/dL). The following study was conducted at the Abbas Institute of Medical Sciences, Muzaffarabad AJK Pakistan. The data was collected through a nonprobability purposive sampling technique. Multivariate analysis was applied using logistic regression to identify specific risk factors for severe anemia.

Results: The mean age of the patients was 34.2 years (SD 10.8), with 60% from low socioeconomic status. The mean iron level was 30.4 (SD 12.5) and the mean vitamin B12 level was 190.3 pg/mL (SD 2.3). 46.7% had a history of chronic diseases, with 20.0% having type 2 diabetes and 13.3% having renal diseases. 26.7% were suffering from infections. Chronic disease history significantly increases the risk (OR 2.50, p=0.004).

Conclusion: The study population had low hemoglobin and iron levels, with a high proportion of patients having chronic diseases. Severe anemia was significantly associated with low iron levels and Vitamin B12 deficiency, chronic diseases, and infections, increasing the risk of severe anemia

 

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Published

2024-11-04

How to Cite

Razia, E.-T.-., Khan, S. A., & Awan, A. K. (2024). Unraveling of Multifactorial Etiology and Risk Factors of Severe Anemia HB ≤ 6 g/dL. Indus Journal of Bioscience Research, 2(02), 197–202. https://doi.org/10.70749/ijbr.v2i02.157